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SickKids Research Institute

Driving clinical impact with every
research question

SickKids Research Institute (RI) is where over 2,000 researchers, trainees, and staff are working together to take on the toughest challenges in child health. As Canada’s largest, hospital-based child health research institute, we conduct and translate groundbreaking research to improve child health outcomes, policy, and clinical care, train the next generation of researchers, and support global scientific communities with knowledge and state-of-the-art facilities.  

Innovation and collaboration across our seven distinct research programs have led to a number of incredible discoveries at SickKids, uncovering the mechanisms and outcomes of childhood disease. And with every research question in the lab, we are driving clinical changes.

By challenging existing care models and maximizing research translation, we’re taking more discoveries from the lab bench to the bedside, making a bigger impact on children’s lives around the world, sooner.

By the numbers

276 scientists

1,018 research trainees

394 project & team investigators

1,126 research support staff

$262.6M research spend

2,099 publications

Explore the Institute

Our Researchers

Meet the researchers working across the spectrum of child health, from basic science at the sub-molecular level, to clinical diagnostics, treatments and prevention.

Our Labs

Browse a list of labs to learn more about the exciting research taking place at SickKids Research Institute.

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Research Training Centre

The Research Training Centre offers trainees hands-on opportunities to contribute to some of the most important research projects in Canada and to work with top scientists.

Staff member sits in front of a microscope while looking at a scientific image on a nearby computer screen

Core Facilities

Learn about our cutting-edge equipment and infrastructure that’s powering new innovation and advancements in care.

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Participate in Clinical Research

As one of Canada's top research hospitals, families that walk through our doors have a chance to participate in clinical research to help address our greatest health challenges.

Clinical Research Services

Clinical Research Services supports quality clinical research by providing research facilities, tools, education and services for SickKids staff and researchers worldwide.

Latest research news

Artistic rendering of a DNA helix

May 30, 2023

Decoding the dark matter of our DNA: Study links genetic variants to blood pressure regulation

SickKids scientists assign function to the non-coding genome and shine a light on the genetics of hypertension.

May 24, 2023

Research team receives over $5 million for Canadian paediatric imaging platform

The Canadian Pediatric Imaging Platform (C-PIP) will harness infrastructure and expertise at three Canadian hospitals to help improve understanding of children’s brain health.

A child hugging a woman who smiles back at the child while on a laptop.

May 19, 2023

U-Link Canada makes it easier to find early phase clinical trials for children with cancer

SickKids-led database provides clinicians and families with the latest information on open clinical trials for children with cancer across Canada.

Research programs

Discover what our researchers are working on across SickKids' seven research programs that cover the spectrum of child health.

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Cell Biology

Cutting-edge methods in cell and molecular biology, biochemistry, and microscopy allow us to understand how cells function, and how these functions go awry in disease states.

Visit Cell Biology

Child Health Evaluative Sciences Research Program icon

Child Health Evaluative Sciences

By conducting and translating research into clinical practice, system, and policy, this research aims to improve the health and well-being of children and their families.

Visit Child Health Evaluative Sciences

Developmental and Stem Cell Biology Research Program icon

Developmental & Stem Cell Biology

Using development genetics, genomics, and stem cell biology, these research teams are developing new therapeutic approaches for children and youth.

Visit Developmental & Stem Cell Biology

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Genetics & Genome Biology

Next-generation genomic sequencing tools are revolutionizing our understanding of disease and approaches to science.

Visit Genetics & Genome Biology

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Molecular Medicine

Researchers are developing new molecular approaches for the prevention, diagnosis, and treatment of human diseases.

Visit Molecular Medicine

Neurosciences and Mental Health Research Program icon

Neurosciences & Mental Health

This research focuses on advancing understanding of the brain to develop novel approaches to therapy and prevention strategies.

Visit Neurosciences & Mental Health

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Translational Medicine

Multidisciplinary teams across SickKids are blending their expertise to facilitate new clinical and biological ideas.

Visit Translational Medicine

More from the Research Institute

Comprised of internationally-recognized leaders in research and innovation, the SickKids Scientific Advisory & Innovation Board (SAIB) supports and provides input on the overall strategic directions for the Research Institute.

View SAIB members

Canada Research Chairs showcase the calibre and diversity of scientists and clinicians working at the SickKids Research Institute.

View Canada Research Chairs

SickKids is home to 48 scientific and academic chairs. See who holds current chairs in Canada.

View Chairs

The SickKids Institutional Research Data Management (RDM) strategy outlines our commitment to fostering sound RDM practices and supporting researchers in following the FAIR principles to make data findable, accessible, interoperable and reusable.  

Learn about RDM at SickKids 

Research Awards & Financial Services (RAFS) supports researchers through the grant lifecycle, from grant applications and contract management, to monitoring and financial reporting.

Learn About RAFS

Contact the Research Institute

For all inquiries about SickKids Research Institute, please contact Jelena Djurkic, Manager, Communications (Research Institute & Strategic Initiatives), Communications & Public Affairs

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