Yiming Wang

Project Investigator, Genetics & Genome Biology

Dr. Yiming Wang is a staff physician and clinical geneticist providing care to children and their families with cancer predisposition syndromes, congenital skin disorders (genodermatoses) and other rare paediatric genetic conditions at The Hospital for Sick Children (SickKids). He is also a passionate teacher for clinical and research trainees at SickKids and the University of Toronto.

Dr. Wang grew up in Nanjing and had his medical training in Beijing. He then moved to Toronto and acquired his PhD at the University of Toronto. He subsequently completed the Medical Genetics and Genomics residency program at the University of Toronto (served as the Chief Resident in 2022).

Research

Dr. Wang’s interdisciplinary research focuses on utilizing novel clinical and research tools to explore the genetics, pathogenesis, diagnosis and management of cancer predisposition syndromes and congenital skin disorders.

Education

• 2018–2023: Resident, Medical Genetics and Genomics Residency Program, University of Toronto, Toronto, Ontario, Canada
• 2017–2018: OIRM-MbD Fellow, Toronto General Hospital, Toronto, Ontario, Canada
• 2009–2015: Doctor of Philosophy (PhD), Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada
• 2004–2009: Doctor of Medicine (MD), Peking Union Medical College, Tsinghua University, Beijing, China
• 2001–2004: Pre-Med Biology diploma, College of Life Sciences, Peking University, Beijing, China

Experience

• 2023–Present: Staff Physician, Division of Clinical and Metabolic Genetics, Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada
• 2023–Present: Project Investigator, Genetics and Genome Biology Program, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada
• 2023–Present: Assistant Professor, Department of Paediatrics, University of Toronto, Toronto, Ontario, Canada
• 2015–2023: Research Associate (Part-Time), Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Ontario, Canada

Achievements

• 2024: Geneticist Teaching Award, The Hospital for Sick Children, Toronto, Ontario, Canada
• 2022: 1st Place – Best Presentation, 15th International Skeletal Dysplasia Society Meeting, Santiago, Chile
• 2022: Joe T. R. Clarke Award for Excellence in Clinical Training, Medical Genetics and Genomics Residency Program, University of Toronto, Toronto, Ontario, Canada
• 2019: Abstract Achievement Award, American Society of Hematology, Orlando, Florida, United States
• 2016: Stuart Alan Hoffman Memorial Prize, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada
• 2015: Gold Award, Canadian Student Health Research Forum, Canadian Institutes of Health Research, Winnipeg, Manitoba, Canada

1. Neves MAD, Ni TT, Mackeigan DT, Shoara AA, Lei X, Slavkovic S, Yu SY, Stratton TW, Gallant RC, Zhang D, Xu XR, Fernandes C, Zhu G, Hu X, Chazot N, Donaldson LW, Johnson PE, Connelly K, Rand M, Wang Y^#, Ni H^#. Salvianolic Acid B Inhibits Thrombosis and Directly Blocks the Thrombin Catalytic Site. Research and Practice in Thrombosis and Haemostasis. 2024 May 17;8(4):102443.
2. Wang Y, Ding Q, Prokopec S, Farncombe KM, Bruce J, Casalino S, McCuaig J, Szybowska M, van Engelen K, Lerner-Ellis J, Pugh TJ, Kim RH. Germline whole genome sequencing in adults with multiple primary tumors. Familial Cancer. 2023 July 22; 22: 513-520.
3. Wang Y, Greenfeld E, Watkins N, Zaidi SH, Marshall C, Shannon P, Roifman M, Chong K, Chitayat D, Stavropoulos DJ, Noor A. Diagnostic yield of genome sequencing for prenatal diagnosis of fetal structural anomalies. Prenatal Diagnosis. 2022 Jun; 42(7): 822-830.
4. Xu X*, Wang Y*, Reheman A, Ju L, Spring CM, Jin JW, Yang H, Chen P, Yang Y, Lei X, Chen Y, Zhang H, Song J, Zhang D, Zhu G, She Y, Cyr T, Liu G, Connelly PW, Freedman J, Tso P, Marchese P, Zhu C, Davidson WS, Ruggeri ZM, Ni H. Apolipoprotein A-IV is a novel ligand of platelet αIIbβ3 integrin and an endogenous inhibitor of thrombosis. Nature Communications. 2018 Sep 6; 9 (1): 1-18.
5. Wang Y, Reheman A, Spring CM, Kalantari J, Marshall AH, Wolberg AS, Gross PL, Weitz JI, Rand ML, Mosher DF, Freedman J, Ni H. Plasma fibronectin supports hemostasis and regulates thrombosis. Journal of Clinical Investigation. 2014 Oct 1; 124(10):4281–4293.

See a full list of Yiming Wang's publications.