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SickKids

Sonia Grandi

Title: Scientist, Child Health Evaluative Sciences
Designations: M.Sc., PhD
Phone: 416-813-7654 ext. 303619
Email: sonia.grandi@sickkids.ca
Alternate Contact Name: Poonam Dodia
Alternate Email: poonam.dodia@sickkids.ca
U of T Positions: Assistant Professor, Division of Epidemiology, Dalla Lana School of Public Health
Other Positions: Junior Editor, Journal of Paediatric and Perinatal Epidemiology

Biography

Sonia Grandi, PhD, is a Scientist at SickKids Research Institute and an Assistant Professor at the University of Toronto in the Division of Epidemiology at the Dalla Lana School of Public Health. She completed her PhD in Epidemiology at McGill University in the Department of Epidemiology, Biostatistics, and Occupational Health and a postdoctoral fellowship at the Eunice Kennedy Shriver National Institutes of Child Health and Human Development at the National Institutes of Health. Her work focused on the consequences of pregnancy complications on long-term maternal cardiovascular disease and mortality and strategies for early identification and screening of at-risk women.

Research

Dr. Grandi’s research focuses on the short- and long-term influence of preconception and perinatal exposures on the health of mothers and children, with a focus on cardiometabolic health. Her research interests include understanding how pregnancy complications and interventions designed to reduce those complications, impact the health of mothers and infants, the safety and effectiveness of medications taken during pregnancy on the health of mothers and their children among women with chronic conditions, and understanding inequities in severe maternal morbidity and mortality and strategies to identify women at highest risk. As a methodologist, Dr. Grandi is interested in the application of contemporary methods and leveraging administrative health data to help inform clinical practice.

Education and experience

  • 2020–2021: Postdoctoral Fellowship, Eunice Shriver Kennedy National Institute of Child Health and Human Development, National Institutes of Health Research, Epidemiology Branch, Bethesda, MD, USA
  • 2013–2019: PhD, Epidemiology, Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada
  • 2003–2007: M.Sc., Nutrition, School of Human Nutrition, McGill University, Montreal, QC, Canada
  • 1996–2001: B.Sc., Human Biology, University of Toronto, Toronto, ON, Canada

Achievements

  • 2023–2026: Junior Editor, Paediatric and Perinatal Epidemiology Journal
  • 2022–2025: Society for Epidemiologic Research, Member of the Mentorship Committee
  • 2020–2021: Society for Pediatric and Perinatal Epidemiologic Research, Elected Member of the Executive Committee
  • 2019: Lady Davis Institute of Medical Research, Paper of the Month, Montreal, QC, Canada
  • 2019: Poster Presentation Prize, First Place: Canadian National Perinatal Research Meeting
  • 2018: Top three most downloaded articles in the last two years, Journal of Pediatric and Perinatal Epidemiology
  • 2017: Oral Presentation Prize, First Place: Department of Epidemiology, Biostatistics, and Occupational Health Research Day, McGill University
  • 2015: Trudy Bush Fellowship for Cardiovascular Disease Research in Women’s Health, American Heart Association

Funding

  • 2023–2025: Aspirin and severe maternal morbidity and mortality and adverse perinatal outcomes. Principal Investigator. Canadian Institutes of Health Research – Project Grant. $294,526 CAD. Co-Principal Investigator: Joel Ray
  • 2023–2025: Impact of Multiple Chronic Conditions on Pregnancy Outcomes. Co-Investigator. Canadian Institutes of Health Research – Operating Grant. $74,993 CAD. Co-Principal Investigators: Hilary Brown and Joel Ray
  • 2023–2025: Childhood Grief in Canada: Understanding Prevalence, Demographics, Disparities, and Quality Indicators for Service Provision. Co-Investigator. Canadian Institutes of Health Research – Operating Grant. $50,000 CAD. Principal Investigator: Kimberley Widger
  • 2022: Cardiometabolic Health of Mothers with a Sick Child. Co-Principal Investigator. Data Sciences Institute, University of Toronto – Data Access Grant. $10,000 CAD. Co-Principal Investigator: Eyal Cohen
  • 2022–2025: The “predicting Short-term Adverse cardiovascular outcomes in preeclampsia using BIomarkers” (SARABI) Pilot Study. Co-Investigator. Canadian Institutes of Health Research – Operating Grant. $650,000 CAD. Co-Principal Investigators: Stella Daskalopoulou, and Isabelle Malhamé
  • 2022–2025: Cardiometabolic Health of Mothers with a Sick Child. Co-Investigator. Canadian Institutes of Health Research – Project Grant. $336,599 CAD. Co-Principal Investigators: Eyal Cohen, and Joel Ray

Publications

  1. Sharma G, Ipek EG, Grandi SM. The Impact of Hypertensive Disorders of Pregnancy on Cardiovascular Outcomes: Flying Under the Radar. Invited Editorial Comment. J Am Coll Cardiol. 2022 May 17;79(19):1914-1916. doi: 10.1016/j.jacc.2022.03.334.
  2. Grandi SM, Hinkle SN, Mumford SL, Sjaarda LA, Grantz KL, Mendola P, Mills JL, Pollack AZ, Yeung E, Zhang C, Schisterman EF. Long-term mortality in women with pregnancy loss and modification by race/ethnicity. Am J Epidemiol. 2022 Mar 24;191(5):787-799. doi: 10.1093/aje/kwac023.
  3. Grandi SM, Filion KB, Hutcheon JA, Rosella LA, Platt RW. Accounting for Repeat Pregnancies in Prediction Models. Epidemiology. 2021; 32(4):560-569. doi:10.1097/EDE. 0000000000001349.
  4. Grandi SM, Filion KB, Yoon S, Ayele HT, Doyle CM, Hutcheon JA, Gore GC, Smith GN, Ray J, Nerenberg K, Platt RW. Cardiovascular Disease-Related Morbidity and Mortality in Women with a History of Pregnancy Complications: A Systematic Review. Circulation. 2019; 139:1069-1079.
  5. Grandi SM, Smith GN, Platt RW. The relative contribution of pregnancy complications to cardiovascular risk prediction: Are we getting it wrong? Circulation. 2019; 140:1965-1967.

See Sonia Grandi's Google Scholar profile. 
See a full list of Sonia Grandi's publications on PubMed. 

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