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Broad Spectrum Drug Screen, plasma or serum

Alternate test name

Blood Drug Screen

Lab area
Clinical Biochemistry - TDM & Toxicology
Method and equipment
LC-MS/MS
Expected turn-around time
Stat: 3 hours Routine: 24 hrs
Specimen type

Serum or plasma

Specimen requirements

2.0 mL

Storage and transportation

4°C (transport with a cool pack if possible)

Background and clinical significance

Screen and confirmation for a wide variety of individual drugs by LC-MS/MS (Liquid chromatography - Mass spectrometry/ Mass spectrometry). Currently there are over 1400 drugs in the Broad Spectrum Drug Library (Parent & Metabolites)

Includes many of the drug classes normally done by immunoassay: Amphetamine/Methamphetamine, Cocaine metabolite, Ecstasy, Methadone/Methadone metabolite, Opiates, Oxycodone, PCP, Trcyclics.

Reported as "Not Detected" or "Positive" based on a minimum concentration of drug being present in the urine to allow for proper identification of the drug by matching the MS (Mass spectrometry) spectra of the unknown compound to the Mass Spectrometry Spectra in the library. Phone the Toxicology Laboratory at 416-813-5906, to check on the availability of any specific drug if not listed here.

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