300 uL Serum or Plasma.
Vitamin E and Vitamin A are tested together and should be in the same aliquot tube, above volumes apply.
- Collect 1mL whole blood, spin, separate and freeze (-20oC)
- Separated within 2 hrs of collection.
- Stored protected from light
- Unacceptable Specimens: Oxalate, citrate and EDTA cause significant losses of vitamin A and E
- Vitamin E and Vitamin A are tested together and should be in the same aliquot tube, above volumes apply.
Stability: 1 month @ -20oC
Patient should be fasted for 12-14 h prior to sample collection.
No vitamin supplement within the previous 24 h.
No alcohol intake within the previous 24 h.
Indicate whether sample is from fasting patient or not.
Deficiency of vitamin E may cause extensive neuropathy in young children and, in addition, is suspect as a possible cause of motor and sensory neuropathy in older children and in adults. One likely cause of vitamin E deficiency is intestinal malabsorption, resulting from bowel disease, pancreatic disease, or chronic cholestasis. Other causes of malabsorption of vitamin E include celiac disease, cystic fibrosis, and intestinal lymphangiectasia.
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