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Vitamin E

Alternate test name

alpha-Tocopherol

Lab area
Clinical Biochemistry - Special
Method and equipment
HPLC
Expected turn-around time
14 days
Specimen type

300 uL Serum or Plasma.

Vitamin E and Vitamin A are tested together and should be in the same aliquot tube, above volumes apply. 

Specimen requirements
  • Collect 1mL whole blood, spin, separate and freeze (-20oC)
  • Separated within 2 hrs of collection.
  • Stored protected from light
  • Unacceptable Specimens: Oxalate, citrate and EDTA cause significant losses of vitamin A and E
  • Vitamin E and Vitamin A are tested together and should be in the same aliquot tube, above volumes apply. 
Storage and transportation

Stability: 1 month @ -20oC

Ship Frozen

Special requirements

Patient should be fasted for 12-14 h prior to sample collection.
No vitamin supplement within the previous 24 h.
No alcohol intake within the previous 24 h.

Indicate whether sample is from fasting patient or not.

Shipping information
The Hospital for Sick Children
Rapid Response Laboratory
555 University Avenue, Room 3642
Toronto, ON
Canada
M5G 1X8
Phone: 416-813-7200
Toll Free: 1-855-381-3212
Hours: 7 days/week, 24 hours/day
Background and clinical significance

Deficiency of vitamin E may cause extensive neuropathy in young children and, in addition, is suspect as a possible cause of motor and sensory neuropathy in older children and in adults. One likely cause of vitamin E deficiency is intestinal malabsorption, resulting from bowel disease, pancreatic disease, or chronic cholestasis. Other causes of malabsorption of vitamin E include celiac disease, cystic fibrosis, and intestinal lymphangiectasia.

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