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Mucopolysaccharides Screen, urine

Alternate test name

MPS screen

Lab area
Clinical Biochemistry - Metabolic Diseases
Method and equipment
Screen for excess mucopolysaccharides in urine by dimethylmethylene blue (DMMB) dye.
Expected turn-around time
10 days
Specimen type

Random Urine

Specimen requirements

15 mL of urine in sterile screw top container

Storage and transportation
  • Store at 4oC. Keep cool during transport.
Special requirements

TLC is performed following a positive mucopolysaccharide screen.

Shipping information
The Hospital for Sick Children
Rapid Response Laboratory
555 University Avenue, Room 3642
Toronto, ON
M5G 1X8
Phone: 416-813-7200
Toll Free: 1-855-381-3212
Hours: 7 days/week, 24 hours/day
Disease condition
  • Hurler Syndrome (MPS Ih)
  • Hurler-Sheie Syndrome (MPS Ih/s)
  • Sheie Syndrome (MPS Is)
  • Hunter Syndrome (MPS II)
  • Sanfilippo Syndrome (MP SIII)
  • Morquio Syndrome (MPS IV)
  • Maroteaux-Lamy Syndrome (MPS VI)
  • Sly Syndrome (MPS VII)
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