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Mathieu Lemaire

Title: Staff Physician, Division of Nephrology
Designations: MDCM, PhD, FRCP(C)
Phone: 416-813-7654 ext. 207566
Alternate Contact Name: Carla Santos
Alternate Phone: 416-813-7654 ext. 201220
Alternate Email:
U of T Positions: Assistant Professor, Department of Paediatrics

Research Positions

Scientist, Cell Biology


Dr. Mathieu Lemaire finished his medical training at McGill University in 2004 and then moved to Toronto to learn Paediatrics at SickKids. After completing his fellowship in Paediatric Nephrology in Toronto, he went to Yale University (New Haven, CT) to pursue a PhD in Investigative Medicine under the guidance of Dr. Richard P. Lifton, with a focus on the genetics of rare paediatric kidney diseases. Dr Lemaire returned to the University of Toronto in 2014 as Assistant Professor of Paediatrics. He joined the Division of Nephrology at SickKids as a Staff Physician, and the Cell Biology program at SickKids Research Institute as Scientist-Track Investigator. He was crossappointed to the Department of Biochemistry and to the Institute of Medical Sciences in 2015.


After finishing his medical training at McGill University and the University of Toronto, Dr. Lemaire did a PhD in Investigative Medicine focused on the genetics of rare paediatric kidney diseases. Work in his lab is currently focused on understanding the pathophysiology of novel forms of atypical hemolytic-uremic syndrome (aHUS) that his group discovered using exome sequencing. One project relates to diacylglycerol kinase epsilon (DGKE) nephropathy and phosphoinositide signaling in endothelial cells. Other projects are focused on studying the function of other genes associated with novel forms of aHUS. Meanwhile, he continues to perform gene discovery studies applied to pediatric patients with a variety of unusual renal phenotypes.

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