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Anti-Liver Kidney Microsomal Antibody
Alternate test name
LKM, ALKM, anti-LKM
Lab area
Clinical Biochemistry - Immunology
Method and equipment
Indirect immunofluorescence (IFA), HEp-2 cell substrate
Expected turn-around time
7 days
Specimen type
Serum
Specimen requirements
Send 0.3 mL for 1 test or 0.6 mL min for several tests from:
- ANA, HEp-2 IgG
- ANCA, IgG
- EMA, IgA
- GBM, IgG
- LKM, IgG
- PCA, IgG
- SMA, IgG
- dsDNA, IgG (Cithidia luciliae)
Storage and transportation
Frozen
Shipping information
The Hospital for Sick Children
Rapid Response Laboratory
555 University Avenue, Room 3642
Toronto, ON
Canada
M5G 1X8
Phone: 416-813-7200
Toll Free: 1-855-381-3212
Hours: 7 days/week, 24 hours/day
Background and clinical significance
An anti-LKM antibody (anti–liver-kidney microsomal antibody or LKM antibody) is any of several autoantibodies that are detected in the serum of patients with different types of acute or chronic liver disease. These antibodies are targeted against antigens of the cytochrome P450 system. ALKM are also used in the diagnosis of autoimmune hepatitis.
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Customer Service
Toll Free: 1-855-381-3212
Local: 416-813-7200