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Alpha-1-Acid glycoprotein (AAG), plasma or serum
Orosomucoid , A1AGP
Chemiluminescent microparticle immunoassay (CMIA) by Abbott Architect
Serum or plasma
SST Tube preferred, PST Tube is acceptable
Specimens may be stored on or off the clot, red blood cells, or separator gel for up to 3 days at room temperature or up to 7 days at 2-8°C. If testing will be delayed more than 7 days, remove serum or plasma from the clot, red blood cells, or separator gel and store at -20°C or colder
A1-acid glycoprotein (AGP, orosomucoid) is an acute-phase protein.
Elevated serum levels of A1-acid glycoprotein have been reported in acute and chronic inflammatory conditions, such as myocardial infarction, rheumatoid arthritis, systemic lupus erythematosus, Crohn's disease, chronic renal failure, injuries, burns, and malignancies.
Decreased serum levels of A1-acid glycoprotein can be found in malnutrition, in severe liver damage as well as in women using oral contraceptives (estrogens).
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