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Turning stem cells into bile duct cells to study ‘disease in a dish’

August 31, 2015

A Toronto team of clinician-scientists and stem cell biologists has developed a powerful new method to generate 3D bile duct structures from human stem cells in order to study and develop new treatments for bile duct diseases.

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SickKids study leads to new practice point for assessing management options for newly diagnosed, typical immune thrombocytopenia

December 20, 2018

Engaging families in shared decision making is essential to examine the benefits and limitations of each treatment option for patients with newly diagnosed, typical immune thrombocytopenia (ITP).

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New genetic tests playing a role in the management of autism spectrum disorder

September 1, 2015

A new study has looked at the diagnostic yield of two newer genetic testing methods among children with autism spectrum disorder (ASD). In some cases, the ASD-associated genetic changes result in targeted medical treatment of the child at an earlier …

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Visualizing the invisible: SickKids scientists determine structure of cellular powerhouse for the first time

October 26, 2017

Published Oct. 26 online in Science, scientists at The Hospital for Sick Children (SickKids) determined the structure of the energy powerhouse within our cells, the mitochondrial ATP synthase, for the first time at sufficient resolution to reveal …

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Mobile media device use is associated with language delay in infants

December 21, 2018

A recent study by researchers at SickKids, published in the Journal of Developmental and Behavioural Pediatrics, revealed a significant association between mobile media device use and expressive speech delay.

Low-income Ontario children with diabetes faring better than their Californian counterparts

December 9, 2016

Low-income children with Type 1 diabetes in Ontario are getting more of the recommended preventative care visits and have fewer hospitalizations than similar children in California, according to a new study.

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Terry Fox Foundation grants $2.2 million to SickKids cancer research

September 16, 2015

Researchers at The Hospital for Sick Children (SickKids) will receive $2.2 million from the Terry Fox Foundation over the next three years to continue their research on a rare cancer predisposition condition called Li-Fraumeni Syndrome.

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Science Show & Tell: Study uncovers three subgroups of rare children’s brain cancer

December 12, 2016

Dr. Annie Huang chats about her SickKids study that uncovered three subgroups of atypical teratoid rhabdoid tumours and identified promising drugs to target each type in the Science Show & Tell series.

SickKids scientist Dr. Norman Rosenblum named Scientific Director of the CIHR Institute of Nutrition, Metabolism and Diabetes

November 8, 2017

The Canadian Institutes of Health Research (CIHR) announced today the appointment of SickKids Senior Scientist Dr. Norman Rosenblum as the new Scientific Director of CIHR’s Institute of Nutrition, Metabolism and Diabetes.

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Topical cream lessens pain in infants receiving vaccinations, study shows

December 12, 2016

Research led by SickKids has found that liposomal lidocaine, a topical pain cream, is an effective method to reduce pain in infants receiving vaccination injections.

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