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SickKids

CMV, EBV, HHV 6 by PCR - Blood

Alternate test name

Cytomegalovirus, Epstein Barr virus, Human herpes virus, Post-transplant lymphoproliferative disease (PTLD)

Gene name / Alternate gene name

DNA polymerase

Lab area
Microbiology - Molecular
Method and equipment
Real-time Polymerase Chain Reaction
Expected turn-around time
Within 4 days
Specimen type
  • Whole blood 
Specimen requirements
  • Whole blood (EDTA) - 1 mL minimum for 1 test;  0.4 mL for each additional PCR test to a maximum of 2mL
Storage and transportation
  • All specimens must be shipped on dry ice.
  • Exception: Specimens that will arrive at SickKids within 24 hours from the time of collection can be shipped on ice packs
Background and clinical significance

 

Disease condition

CMV: 

  • Neonatal infection
  • Disseminated infection
  • Monitoring of transplant patients

EBV:

  • EBV reactivation post transplant
  • post-transplant lymphoproliferative disease (PTLD)
  • Monitoring of transplant patients

HHV6 A/B:

  • Monitoring of transplant patients
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